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Injection-based treatments for peyronies disease
Page reviewed by Consultant Urologists April 2026
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What are injection-based treatments for Peyronie’s disease?
Injection-based treatments for Peyronie’s disease may be considered for selected patients, particularly during the early or active stage of the condition. This treatment involves injecting medication directly into the area of scar tissue, or plaque, within the penis with the aim of influencing the structure of the plaque and reducing curvature.
For some patients, injection treatment may help improve symptoms and penile shape, depending on the nature and severity of the condition. Treatment is usually carried out as a course over several sessions, often spaced two to four weeks apart, based on clinical assessment and individual response.
Potential Benefits of Injection-Based Treatments for Peyronie’s Disease
For selected patients, injection-based treatments for Peyronie’s disease may help improve symptoms and penile curvature as part of a tailored management plan. The potential benefits depend on the stage of the condition, the nature of the plaque, and the individual clinical picture.
- May help reduce plaque firmness
- May help improve penile curvature
- May help alleviate discomfort associated with Peyronie’s disease
- May support symptom improvement without immediate surgery
- Can be considered as part of a broader non-surgical treatment approach
Outcomes vary between individuals, and not every patient will respond in the same way. A specialist consultation can help determine whether injection-based treatment may be appropriate in your case.
Is Injection Therapy Right for You?
Injection therapy may be suitable for some patients with Peyronie’s disease, particularly where a non-surgical approach is preferred and the condition is assessed at an earlier stage. Treatment recommendations should always be based on a full assessment by an experienced urologist.
- Early-stage Peyronie’s disease with mild to moderate curvature
- Mild discomfort or pain during erection
- Preference for a non-surgical treatment option
- Interest in a treatment plan that may be combined with PRP treatment or shockwave therapy
- Selected cases where treatment may help delay or reduce the need for surgery
Where appropriate, injection therapy can be considered alongside PRP treatment or shockwave therapy as part of a personalised treatment plan. If you would like to understand which option may be most suitable, a confidential consultation can provide a clearer assessment based on your symptoms and goals.
Procedure Overview
Injection-based treatment for Peyronie’s disease is typically carried out in an outpatient setting and is generally well tolerated. The exact treatment plan can vary depending on the severity of the condition and the clinical assessment.
- Anaesthetic: Local
- Treatment time: Approximately 15–30 minutes
- Number of sessions: Usually 4–8, spaced a few weeks apart
- Recovery: Most patients can resume normal activities shortly afterwards
Some men experience mild discomfort at the injection site, but the procedure is generally well tolerated.
Combining Peyronie’s Disease Injections with Other Treatments
In some cases, injection-based treatment for Peyronie’s disease may be used alongside other therapies as part of a broader treatment plan. This approach can be considered where a combination of treatments is felt to be more appropriate based on the stage of the condition and the patient’s symptoms.
- PRP therapy may be considered as part of a treatment plan aimed at supporting tissue repair
- Shockwave therapy may be used in selected cases where pain relief and tissue stimulation are treatment goals
- Plaque incision and grafting surgery may be considered for patients whose curvature progresses and becomes more established
For a fuller overview of available options, visit our Peyronie’s Disease Hub. A specialist consultation can help determine whether injection therapy alone or as part of a combined approach may be more suitable for you.
What results can injections achieve ?
Injections may reduce plaque hardness and curvature, improve tissue flexibility, and slow disease progression in early or active stages
Some men see improvement within weeks , while others may need adjunctive treatments like PRP or surgery for optimal results.
Read our in-depth article about injections for peyronies disease and learn more about the potenetial results, side effects and limitations
Risks and Limitations
As with all medical treatments there are potential risks and limitations
These may include
Temporary discomfort at the injection site
Bruising or swelling
Limited or variable effectivness
The need for repeat treatment
In some cases patients with more advanced curvature , or those in the stable phase of the disease, may be better suited to surgical management.
Related Pages
Learn more about PRP therapy for peyronies disease
Explore shockwave therapy for peyronies disease
Surgical options if injections are not effective
A Specialist Approach
At Moorgate Andrology, treatment decisions are based on careful assessment to determine the most appropriate approach for each patient, whether non-surgical or surgeical
Take the Next Step
If you have early-stage Peyronie’s Disease and want to soften plaques or slow curvature progression, injection therapy for Moorgate Andrology offer a safe, minimally invasive option.
Book your private consultation today to explore personalised treatment options.
Interest Free Finance
Spread the cost of your treatment over one year, no deposit required.
- Simple two minute application.
- Affordable monthly payments
- Quick decision.
- Application help from our team
- Finance available up to £5,000 with Pay It Monthly – no deposit required.
Book a consultation today and find out how you can pay for your treatment in 12 easy installments.
Book Your Free Consultation Now
Understanding your treatment options begins with a conversation. By filling in the contact form, you can book a completely free consultation with a Urologist.
During the call, they’ll:
- Answer your questions
- Discuss your goals
- Explain the treatment process
We are committed to giving you clear, expert guidance every step of the way.
Talk To Our Team
Book A Free Urologist Consultation
Moorgate has a network of nationwide surgeons and centres , simply find your convenient location below:
64 Harley St, Marylebone, London,W1G 7HB
356 Ecclesall Rd South Sheffield,S11 9PU
Durton Lane, Broughton, Preston PR3 5LD
Westland Avenue, Hornchurch. Essex. RM11 3SD
Frequently Asked Questions
Most men feel only mild discomfort during the injection. Local anaesthetic can be used if needed.
Treatment typically involves 4–8 sessions, depending on plaque severity and disease stage.
These injections may improve curvature but is less effective for severe or stable-phase Peyronie’s Disease, where surgery may be required.
Yes — combination therapy often improves results in early-stage disease.
Some men see changes in plaque softness and curvature within a few weeks of starting treatment.
We cannot guarantee results. Much depends on your response to treatment. In most cases the treatment does improve the condition. If you do not respond as well as anticipated, you may need to consider other options such as a surgical resolution. Our Urologists will discuss this with you in such a case.
Other treatments include platelet rich plasma (PRP) treatments. Shockwave therapy can be useful where there is pain on erection but there is little evidence that it helps improve curvature. Surgery options could be considered which will make the penis straight again. You can discuss these with the Urologist at your consultation.
Injection therapy may slow progression to soften the plaque, but it does not guarantee avoidance of surgery. A specialist consultation determines the best plan based on your individual condition.
These usually involve a series of injection treatments to soften the scar tissue and help improve penile curvature. They are not suitable for every case but they can be particularly helpful in the early stage of the disease
Most patients do not experience any issues after treatment and are able to return to normal activities. Occasionally some mild bruising or selling at the injection site may be noticed
All treatments are performed by Specialist Urologists with experience in the treatment of peyronies disease
This treatment is available in Central London, Preston, Manchester and Sheffield
