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Injection-based treatments for peyronies disease
Page reviewed by Consultant Urologists April 2026
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What are Injection-based treatments for peyronies disease ?
Injection-based treatments may be considered for certain patients with peyronies disease, particularly in early or active stages of the condition.
The treatment involves the targeted administration of medication directly into the area of the scar tissue ( plaque) within the penis.
The aim is to influence the structure of the plaque within the penis.
This can help reduce curvature and improve symptoms.
Injection-based treatment is typically performed as a course of treatment over a number of different sessions, typically two to four weeks apart, depending on individual response and clinical assessment.
Potential benefits of Injections for peyronies disease
In selected cases, injection-based treatment may help
Reduce plaque firmness
Improve penile curvature
Alleviate discomfort associated with the condition.
Outcomes can vary between individuals and not all patients will respond in the same way
Is Injection therapy right for you ?
Early stage peyronies disease with mild to moderate curvature
Mild discomfort or pain on erection
Prefer a non-surgical approach
Can be combined with PRP or shockwave therapy
Can delay or reduce the need for surgery
Can be used as part of a combination approach with PRP ( Platelet -Rich-plasma) or Shockwave therapy
Procedure Overview
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Anaesthetic: Local
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Treatment time: 15–30 minutes
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Number of sessions: Usually 4–8, spaced a few weeks apart
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Recovery: Resume normal activities immediately
Most men experience only mild discomfort at the injection site, and the procedure is well tolerated.
Combining peyronies disease Injections with Other Treatments
injections can sometimes work best when combined with:
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PRP Therapy – to accelerate tissue repair
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Shockwave Therapy – to relieve pain and stimulate healing
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Plaque Incision and Grafting Surgery – for men whose curvature progresses to the stable phase
Visit our Peyronie’s Disease Hub for details on all treatment options.
What results can injections achieve ?
Injections may reduce plaque hardness and curvature, improve tissue flexibility, and slow disease progression in early or active stages
Some men see improvement within weeks , while others may need adjunctive treatments like PRP or surgery for optimal results
Risks and Limitations
As with all medical treatments there are potential risks and limitations
These may include
Temporary discomfort at the injection site
Bruising or swelling
Limited or variable effectivness
The need for repeat treatment
In some cases patients with more advanced curvature , or those in the stable phase of the disease, may be better suited to surgical management.
Related Pages
Learn more about PRP therapy for peyronies disease
Explore shockwave therapy for peyronies disease
Surgical options if injections are not effective
A Specialist Approach
At Moorgate Andrology, treatment decisions are based on careful assessment to determine the most appropriate approach for each patient, whether non-surgical or surgeical
Take the Next Step
If you have early-stage Peyronie’s Disease and want to soften plaques or slow curvature progression, injection therapy for Moorgate Andrology offer a safe, minimally invasive option.
Book your private consultation today to explore personalised treatment options.
Interest Free Finance
Spread the cost of your treatment over one year, no deposit required.
- Simple two minute application.
- Affordable monthly payments
- Quick decision.
- Application help from our team
- Finance available up to £5,000 with Pay It Monthly – no deposit required.
Book a consultation today and find out how you can pay for your treatment in 12 easy installments.
Book Your Free Consultation Now
Understanding your treatment options begins with a conversation. By filling in the contact form, you can book a completely free consultation with a Urologist.
During the call, they’ll:
- Answer your questions
- Discuss your goals
- Explain the treatment process
We are committed to giving you clear, expert guidance every step of the way.
Talk To Our Team
Book A Free Urologist Consultation
Moorgate has a network of nationwide surgeons and centres , simply find your convenient location below:
64 Harley St, Marylebone, London,W1G 7HB
356 Ecclesall Rd South Sheffield,S11 9PU
Durton Lane, Broughton, Preston PR3 5LD
Westland Avenue, Hornchurch. Essex. RM11 3SD
Frequently Asked Questions
Most men feel only mild discomfort during the injection. Local anaesthetic can be used if needed.
Treatment typically involves 4–8 sessions, depending on plaque severity and disease stage.
These injections may improve curvature but is less effective for severe or stable-phase Peyronie’s Disease, where surgery may be required.
Yes — combination therapy often improves results in early-stage disease.
Some men see changes in plaque softness and curvature within a few weeks of starting treatment.
We cannot guarantee results. Much depends on your response to treatment. In most cases the treatment does improve the condition. If you do not respond as well as anticipated, you may need to consider other options such as a surgical resolution. Our Urologists will discuss this with you in such a case.
Other treatments include platelet rich plasma (PRP) treatments. Shockwave therapy can be useful where there is pain on erection but there is little evidence that it helps improve curvature. Surgery options could be considered which will make the penis straight again. You can discuss these with the Urologist at your consultation.
Injection therapy may slow progression to soften the plaque, but it does not guarantee avoidance of surgery. A specialist consultation determines the best plan based on your individual condition.
These usually involve a series of injection treatments to soften the scar tissue and help improve penile curvature. They are not suitable for every case but they can be particularly helpful in the early stage of the disease
Most patients do not experience any issues after treatment and are able to return to normal activities. Occasionally some mild bruising or selling at the injection site may be noticed
All treatments are performed by Specialist Urologists with experience in the treatment of peyronies disease
This treatment is available in Central London, Preston, Manchester and Sheffield
