Blog - Moorgate Andrology and Gynaecology

Peyronies disease; Causes and risk factors

Written by David Mills | Nov 3, 2025 1:32:49 PM

Peyronie’s disease is a condition affecting the penis that can cause curvature, pain, and erectile difficulties. Understanding the causes and risk factors can help men seek treatment early and prevent progression.

Common Causes

  • Penile trauma: Even minor injuries during sexual activity or sports

  • Genetic predisposition: Some men may have a connective tissue susceptibility

  • Age-related changes: Men over 40 are more commonly affected

  • Autoimmune factors: Rarely, immune system reactions can contribute

Peyronie’s Disease 

Risk Factors

  • Smoking or vascular disease

  • Diabetes or metabolic syndrome

  • Previous penile surgery

  • Certain medications affecting connective tissue

Internal link: Injectable Treatments

Why Knowing Your Risk Matters

  • Early awareness allows for prompt consultation

  • Non-surgical treatments are more effective in early stages

  • Monitoring symptoms reduces complications and anxiety

Conclusion

If you notice penile curvature, pain, or nodules, consult a urologist promptly. Understanding the causes and risk factors helps guide treatment and improve outcomes.

Recovery & Aftercare